Restylane Restylane is natural cosmetic dermal filler that is used to restore volume and fullness to the skin and to correct moderate to severe facial wrinkles and folds. It can also be used for lip enhancement. Restylane is made of hyaluronic acid, which is a natural body substance. The FDA approved the use of Restylane in February 2004. It has been used in Europe and Canada for several years. Restylane injection is an office procedure. Injection can be painful and therefore, either a dental type local anesthetic block is performed or anesthetic cream is applied before the injection. Some patients have bruising and swelling after injection that can take a few days to resolve. It’s best not to schedule your treatment the day before that 30th high school reunion. Restylane usually lasts about 6 months. No pretesting is required. Please give the office a call if you are interested in trying this new filler substance. For more information, check out their web site at www.restylaneusa.com.